Fwd: PNAS Early Edition for 4 Feb 2015

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Proceedings of the National Academy of Sciences Early Edition articles for 4 February 2015 Letters (Online Only) Role of dairy in the carbon footprint of US beef Nicole Tichenor Reply to Tichenor: Proposed update to beef greenhouse gas footprint is numerically questionable and well within current uncertainty bounds Gidon Eshel, Alon Shepon, Tamar Makov, and Ron Milo Retrospective Donald Metcalf: The father of modern hematology Jerry M. Adams and Suzanne Cory Commentaries Birds tune in to sequential information when categorizing their songs Julia Fischer Chemical proteomics reveals a second family of cyclic-di-AMP hydrolases John D. Helmann Perspective Building coral reef resilience through assisted evolution  Madeleine J. H. van Oppen, James K. Oliver, Hollie M. Putnam, and Ruth D. Gates Dark Matter Universe: On the Threshold of Discovery Sackler Colloquium (free online) Physical Sciences — Astronomy Cold dark matter: Controversies on small scales David H. Weinberg, James S. Bullock, Fabio Governato, Rachel Kuzio de Naray, and Annika H. G. Peter Physical Sciences Applied Physical Sciences The spontaneous emergence of conventions: An experimental study of cultural evolution Damon Centola and Andrea Baronchelli Suppression of phase separation and giant enhancement of superconducting transition temperature in FeSe1−xTex thin films Yoshinori Imai, Yuichi Sawada, Fuyuki Nabeshima, and Atsutaka Maeda Chemistry Elucidation of synaptonemal complex organization by super-resolution imaging with isotropic resolution  Katharina Schücker, Thorge Holm, Christian Franke, Markus Sauer, and Ricardo Benavente Metal-free organic sensitizers for use in water-splitting dye-sensitized photoelectrochemical cells John R. Swierk, Dalvin D. Méndez-Hernández, Nicholas S. McCool, Paul Liddell, Yuichi Terazono, Ian Pahk, John J. Tomlin, Nolan V. Oster, Thomas A. Moore, Ana L. Moore, Devens Gust, and Thomas E. Mallouk Earth, Atmospheric, and Planetary Sciences Droplet fragmentation: 3D imaging of a previously unidentified pore-scale process during multiphase flow in porous media Tannaz Pak, Ian B. Butler, Sebastian Geiger, Marinus I. J. van Dijke, and Ken S. Sorbie Sulfur-cycling fossil bacteria from the 1.8-Ga Duck Creek Formation provide promising evidence of evolution's null hypothesis J. William Schopf, Anatoliy B. Kudryavtsev, Malcolm R. Walter, Martin J. Van Kranendonk, Kenneth H. Williford, Reinhard Kozdon, John W. Valley, Victor A. Gallardo, Carola Espinoza, and David T. Flannery Engineering Gold–silica quantum rattles for multimodal imaging and therapy Mathew Hembury, Ciro Chiappini, Sergio Bertazzo, Tammy L. Kalber, Glenna L. Drisko, Olumide Ogunlade, Simon Walker-Samuel, Katla Sai Krishna, Coline Jumeaux, Paul Beard, Challa S. S. R. Kumar, Alexandra E. Porter, Mark F. Lythgoe, Cédric Boissière, Clément Sanchez, and Molly M. Stevens Highly multiplexed profiling of single-cell effector functions reveals deep functional heterogeneity in response to pathogenic ligands Yao Lu, Qiong Xue, Markus R. Eisele, Endah S. Sulistijo, Kara Brower, Lin Han, El-ad David Amir, Dana Pe'er, Kathryn Miller-Jensen, and Rong Fan Dynamic phototuning of 3D hydrogel stiffness Ryan S. Stowers, Shane C. Allen, and Laura J. Suggs Physics Magnetic nanopantograph in the SrCu2(BO3)2 Shastry–Sutherland lattice Guillaume Radtke, Andrés Saúl, Hanna A. Dabkowska, Myron B. Salamon, and Marcelo Jaime Penta-graphene: A new carbon allotrope Shunhong Zhang, Jian Zhou, Qian Wang, Xiaoshuang Chen, Yoshiyuki Kawazoe, and Puru Jena Classification of charge density waves based on their nature  Xuetao Zhu, Yanwei Cao, Jiandi Zhang, E. W. Plummer, and Jiandong Guo Scaling laws describe memories of host–pathogen riposte in the HIV population John P. Barton, Mehran Kardar, and Arup K. Chakraborty Sustainability Science Rapid loss of lakes on the Mongolian Plateau Shengli Tao, Jingyun Fang, Xia Zhao, Shuqing Zhao, Haihua Shen, Huifeng Hu, Zhiyao Tang, Zhiheng Wang, and Qinghua Guo Social Sciences Psychological and Cognitive Sciences Role of the motor system in language knowledge Iris Berent, Anna-Katharine Brem, Xu Zhao, Erica Seligson, Hong Pan, Jane Epstein, Emily Stern, Albert M. Galaburda, and Alvaro Pascual-Leone Self-affirmation alters the brain's response to health messages and subsequent behavior change Emily B. Falk, Matthew Brook O'Donnell, Christopher N. Cascio, Francis Tinney, Yoona Kang, Matthew D. Lieberman, Shelley E. Taylor, Lawrence An, Kenneth Resnicow, and Victor J. Strecher Social Sciences The spontaneous emergence of conventions: An experimental study of cultural evolution Damon Centola and Andrea Baronchelli Validating vignette and conjoint survey experiments against real-world behavior  Jens Hainmueller, Dominik Hangartner, and Teppei Yamamoto Biological Sciences Applied Biological Sciences Tunable control of antibody immobilization using electric field Sam Emaminejad, Mehdi Javanmard, Chaitanya Gupta, Shuai Chang, Ronald W. Davis, and Roger T. Howe Glycosylation profiles determine extravasation and disease-targeting properties of armed antibodies Dario Venetz, Christian Hess, Chia-wei Lin, Markus Aebi, and Dario Neri Building coral reef resilience through assisted evolution  Madeleine J. H. van Oppen, James K. Oliver, Hollie M. Putnam, and Ruth D. Gates Dynamic phototuning of 3D hydrogel stiffness Ryan S. Stowers, Shane C. Allen, and Laura J. Suggs Biochemistry Copper economy in Chlamydomonas: Prioritized allocation and reallocation of copper to respiration vs. photosynthesis   Janette Kropat, Sean D. Gallaher, Eugen I. Urzica, Stacie S. Nakamoto, Daniela Strenkert, Stephen Tottey, Andrew Z. Mason, and Sabeeha S. Merchant A CaMKII/PDE4D negative feedback regulates cAMP signaling Delphine Mika, Wito Richter, and Marco Conti Distinct activation of an E2 ubiquitin-conjugating enzyme by its cognate E3 ligases Itamar Cohen, Reuven Wiener, Yuval Reiss, and Tommer Ravid Mitochondrial peroxiredoxin functions as crucial chaperone reservoir in Leishmania infantum Filipa Teixeira, Helena Castro, Tânia Cruz, Eric Tse, Philipp Koldewey, Daniel R. Southworth, Ana M. Tomás, and Ursula Jakob Distinct pathways of RNA polymerase regulation by a phage-encoded factor Daria Esyunina, Evgeny Klimuk, Konstantin Severinov, and Andrey Kulbachinskiy Inhibition of the β-barrel assembly machine by a peptide that binds BamD Christine L. Hagan, Joseph S. Wzorek, and Daniel Kahne Archaeal replicative primases can perform translesion DNA synthesis  Stanislaw K. Jozwiakowski, Farimah Borazjani Gholami, and Aidan J. Doherty Structural basis for transcription reactivation by RapA Bin Liu, Yuhong Zuo, and Thomas A. Steitz A conserved amphipathic helix is required for membrane tubule formation by Yop1p  Jacob P. Brady, Jolyon K. Claridge, Peter G. Smith, and Jason R. Schnell Biophysics and Computational Biology Molecular mechanisms underlying the effect of the novel BK channel opener GoSlo: Involvement of the S4/S5 linker and the S6 segment Timothy I. Webb, Aravind Singh Kshatri, Roddy J. Large, Adebola Morayo Akande, Subhrangsu Roy, Gerard P. Sergeant, Noel G. McHale, Keith D. Thornbury, and Mark A. Hollywood CryoEM and mutagenesis reveal that the smallest capsid protein cements and stabilizes Kaposi's sarcoma-associated herpesvirus capsid Xinghong Dai, Danyang Gong, Yuchen Xiao, Ting-Ting Wu, Ren Sun, and Z. Hong Zhou Proton-coupled electron transfer and the role of water molecules in proton pumping by cytochrome c oxidase Vivek Sharma, Giray Enkavi, Ilpo Vattulainen, Tomasz Róg, and Mårten Wikström Single liposome analysis of peptide translocation by the ABC transporter TAPL Tina Zollmann, Gemma Moiset, Franz Tumulka, Robert Tampé, Bert Poolman, and Rupert Abele Absence of knots in known RNA structures Cristian Micheletti, Marco Di Stefano, and Henri Orland Scaling laws describe memories of host–pathogen riposte in the HIV population John P. Barton, Mehran Kardar, and Arup K. Chakraborty Phylogenomics with paralogs Marc Hellmuth, Nicolas Wieseke, Marcus Lechner, Hans-Peter Lenhof, Martin Middendorf, and Peter F. Stadler Elucidation of synaptonemal complex organization by super-resolution imaging with isotropic resolution  Katharina Schücker, Thorge Holm, Christian Franke, Markus Sauer, and Ricardo Benavente Residue-level resolution of alphavirus envelope protein interactions in pH-dependent fusion Xiancheng Zeng, Suchetana Mukhopadhyay, and Charles L. Brooks III Cell Biology Autoinhibition and relief mechanism for Polo-like kinase 4 Joseph E. Klebba, Daniel W. Buster, Tiffany A. McLamarrah, Nasser M. Rusan, and Gregory C. Rogers Genome-wide targeting of the epigenetic regulatory protein CTCF to gene promoters by the transcription factor TFII-I  Rodrigo Peña-Hernández, Maud Marques, Khalid Hilmi, Teijun Zhao, Amine Saad, Moulay A. Alaoui-Jamali, Sonia V. del Rincon, Todd Ashworth, Ananda L. Roy, Beverly M. Emerson, and Michael Witcher Aged insulin granules display reduced microtubule-dependent mobility and are disposed within actin-positive multigranular bodies  Peter Hoboth, Andreas Müller, Anna Ivanova, Hassan Mziaut, Jaber Dehghany, Anke Sönmez, Martina Lachnit, Michael Meyer-Hermann, Yannis Kalaidzidis, and Michele Solimena The autophagic machinery ensures nonlytic transmission of mycobacteria Lilli Gerstenmaier, Rachel Pilla, Lydia Herrmann, Hendrik Herrmann, Monica Prado, Geno J. Villafano, Margot Kolonko, Rudolph Reimer, Thierry Soldati, Jason S. King, and Monica Hagedorn Developmental Biology Adipogenesis and epicardial adipose tissue: A novel fate of the epicardium induced by mesenchymal transformation and PPARγ activation Yukiko Yamaguchi, Susana Cavallero, Michaela Patterson, Hua Shen, Jian Xu, S. Ram Kumar, and Henry M. Sucov Ecology DNA barcoding and metabarcoding of standardized samples reveal patterns of marine benthic diversity  Matthieu Leray and Nancy Knowlton Environmental Sciences Breakdown of coral colonial form under reduced pH conditions is initiated in polyps and mediated through apoptosis Hagit Kvitt, Esti Kramarsky-Winter, Keren Maor-Landaw, Keren Zandbank, Ariel Kushmaro, Hanna Rosenfeld, Maoz Fine, and Dan Tchernov Evolution Bacterial proteins pinpoint a single eukaryotic root Romain Derelle, Guifré Torruella, Vladimír Klimeš, Henner Brinkmann, Eunsoo Kim, Čestmír Vlček, B. Franz Lang, and Marek Eliáš Matching times of leading and following suggest cooperation through direct reciprocity during V-formation flight in ibis  Bernhard Voelkl, Steven J. Portugal, Markus Unsöld, James R. Usherwood, Alan M. Wilson, and Johannes Fritz Rate of language evolution is affected by population size Lindell Bromham, Xia Hua, Thomas G. Fitzpatrick, and Simon J. Greenhill Crossovers are associated with mutation and biased gene conversion at recombination hotspots  Barbara Arbeithuber, Andrea J. Betancourt, Thomas Ebner, and Irene Tiemann-Boege Sulfur-cycling fossil bacteria from the 1.8-Ga Duck Creek Formation provide promising evidence of evolution's null hypothesis J. William Schopf, Anatoliy B. Kudryavtsev, Malcolm R. Walter, Martin J. Van Kranendonk, Kenneth H. Williford, Reinhard Kozdon, John W. Valley, Victor A. Gallardo, Carola Espinoza, and David T. Flannery Dynamics of gene circuits shapes evolvability  Alba Jiménez, Andreea Munteanu, and James Sharpe Genetics Haploinsufficiency screen highlights two distinct groups of ribosomal protein genes essential for embryonic stem cell fate  Simon Fortier, Tara MacRae, Mélanie Bilodeau, Tobias Sargeant, and Guy Sauvageau Double-stranded RNA made in C. elegans neurons can enter the germline and cause transgenerational gene silencing Sindhuja Devanapally, Snusha Ravikumar, and Antony M. Jose NADPH oxidase 4 is a critical mediator in Ataxia telangiectasia disease  Urbain Weyemi, Christophe E. Redon, Towqir Aziz, Rohini Choudhuri, Daisuke Maeda, Palak R. Parekh, Michael Y. Bonner, Jack L. Arbiser, and William M. Bonner Immunology and Inflammation Noninvasive mapping of pancreatic inflammation in recent-onset type-1 diabetes patients Jason L. Gaglia, Mukesh Harisinghani, Iman Aganj, Gregory R. Wojtkiewicz, Sandeep Hedgire, Christophe Benoist, Diane Mathis, and Ralph Weissleder IL-4 abrogates TH17 cell-mediated inflammation by selective silencing of IL-23 in antigen-presenting cells  Emmanuella Guenova, Yuliya Skabytska, Wolfram Hoetzenecker, Günther Weindl, Karin Sauer, Manuela Tham, Kyu-Won Kim, Ji-Hyeon Park, Ji Hae Seo, Desislava Ignatova, Antonio Cozzio, Mitchell P. Levesque, Thomas Volz, Martin Köberle, Susanne Kaesler, Peter Thomas, Reinhard Mailhammer, Kamran Ghoreschi, Knut Schäkel, Boyko Amarov, Martin Eichner, Martin Schaller, Rachael A. Clark, Martin Röcken, and Tilo Biedermann Aberrant recombination and repair during immunoglobulin class switching in BRCA1-deficient human B cells  Andrea Björkman, Per Qvist, Likun Du, Margarita Bartish, Apostolos Zaravinos, Konstantinos Georgiou, Anders D. Børglum, Richard A. Gatti, Therese Törngren, and Qiang Pan-Hammarström The SWI/SNF chromatin remodeling complex regulates germinal center formation by repressing Blimp-1 expression Jinwook Choi, Shin Jeon, Seungjin Choi, Kyungsoo Park, and Rho Hyun Seong Overlapping hotspots in CDRs are critical sites for V region diversification  Lirong Wei, Richard Chahwan, Shanzhi Wang, Xiaohua Wang, Phuong T. Pham, Myron F. Goodman, Aviv Bergman, Matthew D. Scharff, and Thomas MacCarthy Macrophages eat cancer cells using their own calreticulin as a guide: Roles of TLR and Btk  Mingye Feng, James Y. Chen, Rachel Weissman-Tsukamoto, Jens-Peter Volkmer, Po Yi Ho, Kelly M. McKenna, Samuel Cheshier, Michael Zhang, Nan Guo, Phung Gip, Siddhartha S. Mitra, and Irving L. Weissman PTEN regulates natural killer cell trafficking in vivo Jeffrey W. Leong, Stephanie E. Schneider, Ryan P. Sullivan, Bijal A. Parikh, Bryan A. Anthony, Anvita Singh, Brea A. Jewell, Timothy Schappe, Julia A. Wagner, Daniel C. Link, Wayne M. Yokoyama, and Todd A. Fehniger Suppression of systemic autoimmunity by the innate immune adaptor STING Shruti Sharma, Allison M. Campbell, Jennie Chan, Stefan A. Schattgen, Gregory M. Orlowski, Ribhu Nayar, Annie H. Huyler, Kerstin Nündel, Chandra Mohan, Leslie J. Berg, Mark J. Shlomchik, Ann Marshak-Rothstein, and Katherine A. Fitzgerald Physical detection of influenza A epitopes identifies a stealth subset on human lung epithelium evading natural CD8 immunity Derin B. Keskin, Bruce B. Reinhold, Guang Lan Zhang, Alexander R. Ivanov, Barry L. Karger, and Ellis L. Reinherz Medical Sciences Gold–silica quantum rattles for multimodal imaging and therapy Mathew Hembury, Ciro Chiappini, Sergio Bertazzo, Tammy L. Kalber, Glenna L. Drisko, Olumide Ogunlade, Simon Walker-Samuel, Katla Sai Krishna, Coline Jumeaux, Paul Beard, Challa S. S. R. Kumar, Alexandra E. Porter, Mark F. Lythgoe, Cédric Boissière, Clément Sanchez, and Molly M. Stevens Adverse childhood experiences and physiological wear-and-tear in midlife: Findings from the 1958 British birth cohort Cristina Barboza Solís, Michelle Kelly-Irving, Romain Fantin, Muriel Darnaudéry, Jérôme Torrisani, Thierry Lang, and Cyrille Delpierre Lengthening and shortening of plasma DNA in hepatocellular carcinoma patients  Peiyong Jiang, Carol W. M. Chan, K. C. Allen Chan, Suk Hang Cheng, John Wong, Vincent Wai-Sun Wong, Grace L. H. Wong, Stephen L. Chan, Tony S. K. Mok, Henry L. Y. Chan, Paul B. S. Lai, Rossa W. K. Chiu, and Y. M. Dennis Lo TCL1 targeting miR-3676 is codeleted with tumor protein p53 in chronic lymphocytic leukemia Veronica Balatti, Lara Rizzotto, Cecelia Miller, Alexey Palamarchuk, Paolo Fadda, Rosantony Pandolfo, Laura Z. Rassenti, Erin Hertlein, Amy S. Ruppert, Arletta Lozanski, Gerard Lozanski, Thomas J. Kipps, John C. Byrd, Carlo M. Croce, and Yuri Pekarsky Microbiology Cross-talk and regulatory interactions between the essential response regulator RpaB and cyanobacterial circadian clock output Javier Espinosa, Joseph S. Boyd, Raquel Cantos, Paloma Salinas, Susan S. Golden, and Asuncion Contreras Novel mixed-linkage β-glucan activated by c-di-GMP in Sinorhizobium meliloti Daniel Pérez-Mendoza, Miguel Ángel Rodríguez-Carvajal, Lorena Romero-Jiménez, Gabriela de Araujo Farias, Javier Lloret, María Trinidad Gallegos, and Juan Sanjuán Characterization of nonprimate hepacivirus and construction of a functional molecular clone Troels K. H. Scheel, Amit Kapoor, Eiko Nishiuchi, Kenny V. Brock, Yingpu Yu, Linda Andrus, Meigang Gu, Randall W. Renshaw, Edward J. Dubovi, Sean P. McDonough, Gerlinde R. Van de Walle, W. Ian Lipkin, Thomas J. Divers, Bud C. Tennant, and Charles M. Rice Noncanonical coproporphyrin-dependent bacterial heme biosynthesis pathway that does not use protoporphyrin Harry A. Dailey, Svetlana Gerdes, Tamara A. Dailey, Joseph S. Burch, and John D. Phillips Quorum sensing and policing of Pseudomonas aeruginosa social cheaters Meizhen Wang, Amy L. Schaefer, Ajai A. Dandekar, and E. Peter Greenberg Differential RNA-seq of Vibrio cholerae identifies the VqmR small RNA as a regulator of biofilm formation Kai Papenfort, Konrad U. Förstner, Jian-Ping Cong, Cynthia M. Sharma, and Bonnie L. Bassler Generation of reactive oxygen species by lethal attacks from competing microbes Tao G. Dong, Shiqi Dong, Christy Catalano, Richard Moore, Xiaoye Liang, and John J. Mekalanos Age-related immune clearance of hepatitis B virus infection requires the establishment of gut microbiota Han-Hsuan Chou, Wei-Hung Chien, Li-Ling Wu, Chi-Hung Cheng, Chen-Han Chung, Jau-Haw Horng, Yen-Hsuan Ni, Hong-Tai Tseng, Dafei Wu, Xuemei Lu, Hurng-Yi Wang, Pei-Jer Chen, and Ding-Shinn Chen Revealing the density of encoded functions in a viral RNA  Nikesh Patel, Eric C. Dykeman, Robert H. A. Coutts, George P. Lomonossoff, David J. Rowlands, Simon E. V. Phillips, Neil Ranson, Reidun Twarock, Roman Tuma, and Peter G. Stockley TCF1 and LEF1 act as T-cell intrinsic HTLV-1 antagonists by targeting Tax Guangyong Ma, Jun-ichirou Yasunaga, Hirofumi Akari, and Masao Matsuoka N2 gas is an effective fertilizer for bioethanol production by Zymomonas mobilis Timothy A. Kremer, Breah LaSarre, Amanda L. Posto, and James B. McKinlay An intermolecular electrostatic interaction controls the prepore-to-pore transition in a cholesterol-dependent cytolysin Kristin R. Wade, Eileen M. Hotze, Michael J. Kuiper, Craig J. Morton, Michael W. Parker, and Rodney K. Tweten Neuroscience Two-photon brightness of azobenzene photoswitches designed for glutamate receptor optogenetics Elizabeth C. Carroll, Shai Berlin, Joshua Levitz, Michael A. Kienzler, Zhe Yuan, Dorte Madsen, Delmar S. Larsen, and Ehud Y. Isacoff Plasma butyrylcholinesterase regulates ghrelin to control aggression  Vicky Ping Chen, Yang Gao, Liyi Geng, Robin J. Parks, Yuan-Ping Pang, and Stephen Brimijoin CRYPTOCHROME-mediated phototransduction by modulation of the potassium ion channel β-subunit redox sensor  Keri J. Fogle, Lisa S. Baik, Jerry H. Houl, Tri T. Tran, Logan Roberts, Nicole A. Dahm, Yu Cao, Ming Zhou, and Todd C. Holmes Behavioral training reverses global cortical network dysfunction induced by perinatal antidepressant exposure Xiaoming Zhou, Jordan Y.-F. Lu, Ryan D. Darling, Kimberly L. Simpson, Xiaoqing Zhu, Fang Wang, Liping Yu, Xinde Sun, Michael M. Merzenich, and Rick C. S. Lin Rescue of homeostatic regulation of striatal excitability and locomotor activity in a mouse model of Huntington's disease  Yumei Cao, David Bartolomé-Martín, Naama Rotem, Carlos Rozas, Shlomo S. Dellal, Marcelo A. Chacon, Bashkim Kadriu, Maria Gulinello, Kamran Khodakhah, and Donald S. Faber Self-affirmation alters the brain's response to health messages and subsequent behavior change Emily B. Falk, Matthew Brook O'Donnell, Christopher N. Cascio, Francis Tinney, Yoona Kang, Matthew D. Lieberman, Shelley E. Taylor, Lawrence An, Kenneth Resnicow, and Victor J. Strecher Network-based metaanalysis identifies HNF4A and PTBP1 as longitudinally dynamic biomarkers for Parkinson's disease Jose A. Santiago and Judith A. Potashkin Pharmacology Regulator of G protein signaling 6 is a critical mediator of both reward-related behavioral and pathological responses to alcohol Adele Stewart, Biswanath Maity, Simon P. Anderegg, Chantal Allamargot, Jianqi Yang, and Rory A. Fisher Physiology A fluid secretion pathway unmasked by acinar-specific Tmem16A gene ablation in the adult mouse salivary gland Marcelo A. Catalán, Yusuke Kondo, Gaspar Peña-Munzenmayer, Yasna Jaramillo, Frances Liu, Sooji Choi, Edward Crandall, Zea Borok, Per Flodby, Gary E. Shull, and James E. Melvin Potassium channelopathy-like defect underlies early-stage cerebrovascular dysfunction in a genetic model of small vessel disease Fabrice Dabertrand, Christel Krøigaard, Adrian D. Bonev, Emmanuel Cognat, Thomas Dalsgaard, Valérie Domenga-Denier, David C. Hill-Eubanks, Joseph E. Brayden, Anne Joutel, and Mark T. Nelson Plant Biology Thioredoxin, a master regulator of the tricarboxylic acid cycle in plant mitochondria Danilo M. Daloso, Karolin Müller, Toshihiro Obata, Alexandra Florian, Takayuki Tohge, Alexandra Bottcher, Christophe Riondet, Laetitia Bariat, Fernando Carrari, Adriano Nunes-Nesi, Bob B. Buchanan, Jean-Philippe Reichheld, Wagner L. Araújo, and Alisdair R. Fernie An early secretory pathway mediated by GNOM-LIKE 1 and GNOM is essential for basal polarity establishment in Arabidopsis thaliana  Siamsa M. Doyle, Ash Haeger, Thomas Vain, Adeline Rigal, Corrado Viotti, Małgorzata Łangowska, Qian Ma, Jiří Friml, Natasha V. Raikhel, Glenn R. Hicks, and Stéphanie Robert Auxin binding protein 1 (ABP1) is not required for either auxin signaling or Arabidopsis development Yangbin Gao, Yi Zhang, Da Zhang, Xinhua Dai, Mark Estelle, and Yunde Zhao Tonoplast CBL–CIPK calcium signaling network regulates magnesium homeostasis in Arabidopsis Ren-Jie Tang, Fu-Geng Zhao, Veder J. Garcia, Thomas J. Kleist, Lei Yang, Hong-Xia Zhang, and Sheng Luan Psychological and Cognitive Sciences Role of the motor system in language knowledge Iris Berent, Anna-Katharine Brem, Xu Zhao, Erica Seligson, Hong Pan, Jane Epstein, Emily Stern, Albert M. Galaburda, and Alvaro Pascual-Leone Sustainability Science Rapid loss of lakes on the Mongolian Plateau Shengli Tao, Jingyun Fang, Xia Zhao, Shuqing Zhao, Haihua Shen, Huifeng Hu, Zhiyao Tang, Zhiheng Wang, and Qinghua Guo Systems Biology Highly multiplexed profiling of single-cell effector functions reveals deep functional heterogeneity in response to pathogenic ligands Yao Lu, Qiong Xue, Markus R. Eisele, Endah S. Sulistijo, Kara Brower, Lin Han, El-ad David Amir, Dana Pe'er, Kathryn Miller-Jensen, and Rong Fan A strategy for tissue self-organization that is robust to cellular heterogeneity and plasticity Alec E. Cerchiari, James C. Garbe, Noel Y. Jee, Michael E. Todhunter, Kyle E. Broaders, Donna M. Peehl, Tejal A. Desai, Mark A. LaBarge, Matthew Thomson, and Zev J. Gartner Corrections Correction for Jeon et al., Human 3D vascularized organotypic microfluidic assays to study breast cancer cell extravasation Correction for Pierce et al., Mapping the unconscious maintenance of a lost first language Correction for Swierk et al., Metal-free organic sensitizers for use in water-splitting dye-sensitized photoelectrochemical cells Retraction Retraction for Zhang et al., Metabolic regulation of SIRT1 transcription via a HIC1:CtBP corepressor complex Open Access From the Cover Inaugural Article Classic Cozzarelli Prize Winner Front Matter This message was sent to pascal.alter@gmail.com. (...) Customer Service * 425 Broadway St * Redwood City, CA 94063 * U.S.A. Copyright © 2015 by the National Academy of Sciences